https://homosaurus.org/v3/homoit0000001 homoit0000001 5-alpha reductase deficiency 5-ARD 2019-05-14 xsd:date 2021-12-08 xsd:date https://homosaurus.org/v3/homoit0000669 Variaciones intersex People with 5-alpha reductase deficiency, abbreviated as 5-ARD, have XY chromosomes, testes, and typical levels of testosterone, but their bodies do not have the enzyme responsible for converting testosterone to the more powerful androgen dihydrotestosterone (DHT). This affects how an individual's external sex characteristics develop, and people born with 5-ARD often have genital differences that are noticed at birth. In adolescence, people with 5-ARD typically develop some features associated with testosterone puberty, and they may experience genital growth at this point.