https://homosaurus.org/v3/homoit0001079 homoit0001079 Partial androgen insensitivity syndrome PAIS 2019-05-14 xsd:date 2021-12-08 xsd:date https://homosaurus.org/v3/homoit0000044 Síndrome de insensibilidad a los andrógenos https://homosaurus.org/v3/homoit0000669 Variaciones intersex People with partial androgen insensitivity (PAIS) have some response to testosterone, but not as much as is typical for people with XY chromosomes without androgen insensitivity. People with PAIS may be born with testes that are undescended or partially descended and with genital differences such as a vaginal opening that is shallower than typical, a phallus that may be perceived as a large clitoris or a small penis, and variations affecting their urethra. They might also be born with genitals that look more like a penis or like a vulva and vagina. In adolescence, people with PAIS may develop some features that are associated with a typical testosterone puberty and others that are associated with a typical estrogen puberty since their body responds to some of the testosterone that their gonads produce while the rest is converted into estrogen.